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	<title>Microbes Archives - InnoHEALTH magazine</title>
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		<title>Post Antibiotic World</title>
		<link>https://innohealthmagazine.com/2019/issues/post-antibiotic-world/</link>
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		<pubDate>Mon, 18 Nov 2019 09:25:20 +0000</pubDate>
				<category><![CDATA[Issues]]></category>
		<category><![CDATA[AMR]]></category>
		<category><![CDATA[antibiotic]]></category>
		<category><![CDATA[antibiotic waste]]></category>
		<category><![CDATA[Antimicrobial resistance]]></category>
		<category><![CDATA[Bacteria]]></category>
		<category><![CDATA[Biological]]></category>
		<category><![CDATA[biomass]]></category>
		<category><![CDATA[bioreactor]]></category>
		<category><![CDATA[Central Drugs Standard Control Organization]]></category>
		<category><![CDATA[DNA]]></category>
		<category><![CDATA[filter]]></category>
		<category><![CDATA[first generation]]></category>
		<category><![CDATA[Food Security and standards authority of India]]></category>
		<category><![CDATA[FSSAI]]></category>
		<category><![CDATA[genes]]></category>
		<category><![CDATA[Global action plan]]></category>
		<category><![CDATA[groundwater]]></category>
		<category><![CDATA[guardian of the world]]></category>
		<category><![CDATA[IMA]]></category>
		<category><![CDATA[Indian Medical Association]]></category>
		<category><![CDATA[Infection]]></category>
		<category><![CDATA[irver water]]></category>
		<category><![CDATA[management of waste water]]></category>
		<category><![CDATA[Medicines]]></category>
		<category><![CDATA[membrane bioreactor]]></category>
		<category><![CDATA[metabolization]]></category>
		<category><![CDATA[Microbes]]></category>
		<category><![CDATA[nanofilteration]]></category>
		<category><![CDATA[NAP]]></category>
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		<category><![CDATA[pharmaceutical industry]]></category>
		<category><![CDATA[Plant]]></category>
		<category><![CDATA[plasmids]]></category>
		<category><![CDATA[Pollution]]></category>
		<category><![CDATA[pond water]]></category>
		<category><![CDATA[public health threat]]></category>
		<category><![CDATA[resistance genes]]></category>
		<category><![CDATA[reverse osmosis]]></category>
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		<category><![CDATA[South East Asia Regional Office]]></category>
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		<category><![CDATA[UNICEF]]></category>
		<category><![CDATA[waste products]]></category>
		<category><![CDATA[Wastewater]]></category>
		<category><![CDATA[wastewater plants]]></category>
		<category><![CDATA[waterbodies]]></category>
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		<category><![CDATA[World Health Assembly]]></category>
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		<guid isPermaLink="false">https://ztt.nrm.mybluehostin.me/innohealthmagazine?p=6759</guid>

					<description><![CDATA[<p>Though most of the antibiotics that are consumed are metabolized by the body, a negligible amount is passed through us as waste</p>
<p>The post <a href="https://innohealthmagazine.com/2019/issues/post-antibiotic-world/">Post Antibiotic World</a> appeared first on <a href="https://innohealthmagazine.com">InnoHEALTH magazine</a>.</p>
]]></description>
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	<p style="text-align: justify !important;">Like the ‘guardians of the galaxy’ the futuristic prospect of this world will be a place where the microbes have become resilient against antibiotics and the fight against infection has ceased to find its way through antibiotics. Though most of the antibiotics that are consumed are metabolized by the body, a negligible amount is passed through us as waste, which is further carried to wastewater treatment plants.</p>
<p><em><strong>Also Read: <a href="https://innohealthmagazine.comwell-being/health-and-oral-health-diseases/">Health and Oral Health Diseases</a></strong></em></p>
<p style="text-align: justify !important;">The basic methodology to clean the wastewater in plants is through membrane bioreactor that uses both biological as well as filtration process where bacteria are acclimatized to consume the waste products and help in metabolization. The antibiotic waste breakdown by bacteria often expresses resistance genes that reduce the effectiveness of the medicines. In the long run, the horizontal gene transfer develops whose expression pass from one generation to the next and the resistance genes gain prominence over the years. With the passing phase, the bacteria grow and thrive itself therefore often giving rise to biomass. The biomass is produced in tonnes by wastewater plants nearly every day. After treatment, they are often disposed of as landfills, fertilizers for agriculture and feed crops for livestock. A minute quantity of resistant bacteria and free-floating DNA often finds its way through effluent of the pharmaceutical industries. The studies have further shown that gene elements called plasmids carry resistance genes for several different types of antibiotics, therefore, resulting in a positive correlation between one type of antibiotic and the resistance gene of another. It creates a dangerous dormant situation that can erupt like an active pandemic under the favourable situation. Plasmids are a thousand times smaller than bacteria and their free-floating nature often surpasses the treatment barriers of the filtration system of the treatment process, therefore making exit through effluents. They further contaminate the surface water and groundwater – the two important sources of drinking water. Researchers have found that even low concentrations of just a single type of antibiotic in the water supply leads to resistance in multiple classes of antibiotics and hence leads to antimicrobial resistance (AMR).</p>
<p><em><strong>Also Read: <a href="https://innohealthmagazine.comissues/indian-states-health-card/">Health Card of Indian States</a></strong></em></p>
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	<p style="text-align: justify !important;">Water, as we all know, is the utmost need of our survival. Human body comprises around 60% water and the fact that less consumption of water leads to various diseases in the future. Apart from facts and figure, one simple question we often forget to inquire is where this water is coming from? Surface water i.e. lakes, rivers and ponds or groundwater i.e. tube wells, bore well, well as these are the two sources that give us a glass of water.</p>
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	<p><em><strong>Also Read: <a href="https://innohealthmagazine.comnewscope/baby-jetliner/">Passenger Gave Birth to a Baby on Jetliner</a></strong></em></p>
<p style="text-align: justify !important;">Our health concern and the credulous brainwash of our mind by the various available water filter present scenario and save our planet from the harmful effect of self-made destruction.Effective treatment and management of wastewater from the pharmaceutical industry will help in overcoming antimicrobial resistance. Advanced treatment methods such as reverse osmosis, nano filtration, and membrane bioreactors have shown to be promising processes for cleaning micro pollutants with nano gram per litre (ng/L) concentration levels.The nation where the trial/testing of most of the antibiotic occurs, there are rarely any constraints implemented on the disposal of pharmaceutical wastewater to the surface water. The current scenario of environmental issue foresees that in the near future there will be scarcity of drinking water and our hope was restored when global challenge was taken to in the market often diverts us from our prime concern of keeping our planet safe from water pollution. The pollution of water bodies has been initiated by us and still we are invariably helping it grow with every passing day. As discussed earlier, the various point sources from domestic to industrial pave the way for antibiotic to contaminate the water bodies. According to the latest report of UNICEF, 2.1 billion people lack the access to clean and safe drinking water.</p>
<p><em><strong>Also Read: <a href="https://innohealthmagazine.comtrends/vision-intraocular-lenses/">Extended range of vision intraocular lenses</a></strong></em></p>
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	<p><strong>How do we remove the problem? What do we do to save ourselves from the harmful effects?</strong></p>
<p style="text-align: justify !important;">The encouraging words of Normal Vincent Peale, American author ‘Every problem has in it the seeds of its own solution. If you don&#8217;t have any problems, you don&#8217;t get any seeds’ gives us the hope that we will successfully overcome the present scenario and save our planet from the harmful effect of self-made destruction.Effective treatment and management of wastewater from the pharmaceutical industry will help in overcoming antimicrobial resistance. Advanced treatment methods such as reverse osmosis, nano filtration, and membrane bioreactors have shown to be promising processes for cleaning micro pollutants with nano gram per litre (ng/L) concentration levels.The nation where the trial/testing of most of the antibiotic occurs, there are rarely any constraints implemented on the disposal of pharmaceutical wastewater to the surface water. The current scenario of environmental issue foresees that in the near future there will be scarcity of drinking water and our hope was restored when global challenge was taken to curb the antimicrobial resistance from environment. Remedial measures taken towards eradication are further discussed.</p>
<p><em><strong>Also Read: <a href="https://innohealthmagazine.comissues/rising-burden-of-non-communicable-diseases/">Rising burden of non-communicable diseases</a></strong></em></p>
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	<p style="text-align: justify !important;"><strong>Political commitments:</strong> International efforts: World Health Organization Jaipur declaration on antimicrobial resistance 2011 recognized AMR as a serious public health threat. With the 2014 WHO Report, the extraordinary rates of AMR prevalent in India came into focus. After this report, joint efforts were made by India and WHO. While WHO labelled AMR as the Flagship Priority area for South East Asia Regional Office (SEARO), the Indian Medical Association launched an awareness programme to train the physicians and sensitize the general public. In 2015, the 68th World Health Assembly decided to incorporate the concept of One Health in the fight against AMR and a Global Action Plan was initiated. All member countries, including India, agreed to frame their own National Action Plans (NAPs) for AMR by 2017.</p>
<p><em><strong>Also Read: <a href="https://innohealthmagazine.comissues/specific-health-situation-of-indian-states/">Specific health situation of Indian states </a></strong></em></p>
<p style="text-align: justify !important;"><strong>National efforts:</strong> The Government of India formulated a Core Working Group on AMR that drafted a NAP for the country. Six strategic priorities were listed in NAP, all of which incorporated considerations for AMR in the environment, directly or indirectly. Further, each strategic priority has defined interventions, activities and outputs, the fulfillment of which is delineated by a timeline projected for the next five years. The NAP, although promising, has not yet come into full action in any of the Indian states so far. To curtail the prevalent malpractice of over-the-counter (OTC) sale of drugs, the Central Drugs Standard Control Organization implemented Schedule H1 in India in 2014. It, however, encompasses only a few selected antimicrobial groups. In June 2017, the Food Safety and Standards Authority of India (FSSAI) published the list of maximum residue levels for antimicrobials in foods prepared from animal, poultry and fish.</p>
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	<p style="text-align: justify !important;"><strong>Health Organization in India:</strong> To know the near-exact extent of AMR, AMR surveillance networks were initiated by the Indian Council of Medical Research (ICMR) and the National Centre for Disease Control (NCDC) in 2013 and 2014, respectively. In 2015, these two organizations along with the support from Centers for Disease Control and Prevention (CDC) USA, started a systematic assessment of the prevailing IPC practices in India with the aim of formulating new guidelines for preventing hospital-acquired infections.</p>
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	<p><em><strong>Also Read: <a href="https://innohealthmagazine.comissues/rising-risks-for-cardiovascular-diseases-diabetes/">Rising risks for cardiovascular diseases &amp; diabetes</a></strong></em></p>
<p style="text-align: justify !important;">These activities, however, cater basically to the emerging AMR in the healthcare settings and do not include special provisions for AMR in the environment. Similarly, the National Health Mission&#8217;s National Health Systems Resource Centre and the National Accreditation Board deal with IPC practices and strengthening of laboratories/hospitals and not with the AMR in the environment per se. The importance of AMR in the environment has been realized recently by the national health authorities and The National Health Policy 2017 calls for a rapid standardization of guidelines regarding antibiotic use, limiting the use of antibiotics as OTC medications, banning or restricting the use of antibiotics as growth promoters in animal livestock, and pharma co-vigilance including prescription audits inclusive of antibiotic usage &#8211; in the hospital and community.</p>
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	<p style="text-align: justify !important;"><strong>Innovative ideas:</strong> The National Health Mission of India started the Swachh Bharat Abhiyan or the Swachh India Mission to improve the basic hygiene and sanitation in all spheres of life. As a part of this massive programme, education was imparted through mass media on the health hazards of open defecation. UNICEF data shows that out of one billion openly defecating people in the world, 60 percent reside in India. It is further argued that it is a behavioural problem with the Indians as other poverty struck nations of Africa and South East Asia did not have the problem of open defecation to this an extent. To deal with such socio-cultural issues, innovative ideas along with mass media are needed in India.</p>
<p><em><strong>Also Read: <a href="https://innohealthmagazine.compersona/how-to-write-healthcare-funding-proposals/">How to write a funding proposal?</a></strong></em></p>
<p style="text-align: justify !important;">So far in India, antimicrobial resistance in the environment has been a topic of least priority. With an ever-increasing threat of AMR in the environment, immediate action is required to halt its progress and spread. A combined effort of multidisciplinary and multi-sectoral approach will be able to eradicate the problem in the near future.</p>
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	<h2>About the author</h2>
<p style="text-align: justify !important;"><em><strong>Dr. Debleena Bhattacharya</strong></em> is an independent researcher. She is presently working as an Assistant Professor in the Department of Environmental Science and Engineering at MEFGI, India. She holds a doctoral degree in Environmental Science from IIT (Indian School of Mines) Dhanbad (India). Her specialisation is in the field of wastewater treatment and biotechnology.</p>
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<p>The post <a href="https://innohealthmagazine.com/2019/issues/post-antibiotic-world/">Post Antibiotic World</a> appeared first on <a href="https://innohealthmagazine.com">InnoHEALTH magazine</a>.</p>
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		<title>Forecast dengue spread</title>
		<link>https://innohealthmagazine.com/2018/innovation/forecast-dengue-spread/</link>
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		<dc:creator><![CDATA[InnoHEALTH Magazine]]></dc:creator>
		<pubDate>Wed, 24 Jan 2018 08:05:41 +0000</pubDate>
				<category><![CDATA[Innovation]]></category>
		<category><![CDATA[Blood]]></category>
		<category><![CDATA[Blood Meal]]></category>
		<category><![CDATA[Disease Forecasting]]></category>
		<category><![CDATA[Dr. Avantika Batish]]></category>
		<category><![CDATA[Dr. Shikha T. Malik]]></category>
		<category><![CDATA[EIP]]></category>
		<category><![CDATA[Extrinsic Incubation Period]]></category>
		<category><![CDATA[Forecast Dengue Spread]]></category>
		<category><![CDATA[IICT]]></category>
		<category><![CDATA[Incubation Period]]></category>
		<category><![CDATA[India Science Wire]]></category>
		<category><![CDATA[Indian Institute of Chemical Technology]]></category>
		<category><![CDATA[Infections]]></category>
		<category><![CDATA[InnoHEALTH Magazine]]></category>
		<category><![CDATA[innovatiocuris]]></category>
		<category><![CDATA[Metabolism]]></category>
		<category><![CDATA[Microbes]]></category>
		<category><![CDATA[Migration]]></category>
		<category><![CDATA[Mosquito]]></category>
		<category><![CDATA[National Institute of Pharmaceutical Education and Research]]></category>
		<category><![CDATA[NIPER]]></category>
		<category><![CDATA[Outbreak of Dengue]]></category>
		<category><![CDATA[Population density]]></category>
		<category><![CDATA[Rainfall]]></category>
		<category><![CDATA[Salivary Glands]]></category>
		<category><![CDATA[University of Liverpool]]></category>
		<category><![CDATA[Virus Transmission]]></category>
		<guid isPermaLink="false">https://ztt.nrm.mybluehostin.me/innohealthmagazine?p=3146</guid>

					<description><![CDATA[<p>Climate-based dengue forecasting model could help in planning effective and efficient disease control operations well in advance and optimize the use of resources meticulously.</p>
<p>The post <a href="https://innohealthmagazine.com/2018/innovation/forecast-dengue-spread/">Forecast dengue spread</a> appeared first on <a href="https://innohealthmagazine.com">InnoHEALTH magazine</a>.</p>
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	<h5 style="text-align: center;"><span style="color: #0071b2;">New method developed To forecast dengue spread</span></h5>
<h5 style="text-align: center;"><span style="color: #0071b2;">By Dr. Shikha T. Malik</span></h5>
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	<p style="text-align: justify !important;">Given its close link with both temperature and rainfall, it is possible to forecast outbreak of dengue. But for such disease forecasting to be effective it should be based on models specific for different climatic zones in the country, a new study has shown. The study has been jointly done by the Hyderabad-based Indian Institute of Chemical Technology (IICT), National Institute of Pharmaceutical Education and Research (NIPER), Guwahati, in collaboration with scientists at the University of Liverpool.</p>
<p style="text-align: justify !important;">Scientists have reached this conclusion after evaluating the relationship of climatic factors in the spread of dengue in different climatic zones in the country – Punjab, Haryana, Rajasthan, Gujarat and Kerala. They focused on changes in a factor called ‘extrinsic incubation period (EIP) of the dengue virus by taking into account daily and monthly mean temperatures in these areas.<br />
The extrinsic incubation period (EIP) is the time taken for incubation of the virus in the mosquito. During this period, after the mosquito draws virus rich blood meal, the virus escapes the gut and passes through the mosquito’s body and reaches it salivary glands. Once this happens, the mosquito is infectious and capable of transmitting the virus to a human host.</p>
<p style="text-align: justify !important;">It has been found that climatic conditions play an important role in EIP. Lower temperatures (17–18 °C) result in longer EIPs thereby leading to decreased virus transmission. With increasing temperatures, feeding increases because of enhanced metabolism of the mosquito, leading to shorter EIPs. Even a 5-day decrease in the incubation period can hike transmission rate by three times, and with an increase in temperature from 17 to 30 °C, dengue transmission increases fourfold. However, a further increase in temperature beyond 35 °C is detrimental to the mosquito survival.<br />
Dr. Shikha T. Malik The researchers observed that except for Gujarat which comprises of arid regions, there was a strong correlation between rainfall and dengue disease burden.</p>
<p style="text-align: justify !important;">The study found that Kerala being warm (temperature range 23.5-30°C) and wet and with short EIPs (9-14 days) experiences the highest number of dengue cases.It has been found that EIP is the shortest during the monsoon season in most states and therefore there is an enhanced risk of dengue during this time.</p>
<p style="text-align: justify !important;">This climate-based dengue forecasting model could help in planning effective and efficient disease control operations well in advance and optimize the use of resources meticulously.</p>
<p style="text-align: justify !important;">With changes in temperature affecting the extrinsic incubation period of the virus, future changes in the climate might have a substantial effect on dengue and other vector borne disease burden in India. “Though such methods are in vogue for disease control operations, we are still in the initial stages of implementation of such strategic control methods,” Dr Rao told India Science Wire. Factors such as population density and migration also need to be included for future risk assessment studies. The study was published in journal Emerging Microbes &amp; Infections.</p>
<h4><em><span style="color: #0071b2;">Article shared from ‘India Science Wire’</span></em></h4>
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	<p><strong>Read all the issues of InnoHEALTH magazine:</strong><br />
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InnoHEALTH Volume 2 Issue 3 (July to September 2017) – <a href="https://goo.gl/MCVjd6">https://goo.gl/MCVjd6</a><br />
InnoHEALTH Volume 2 Issue 4 (October to December 2017) – <a href="http://amzn.to/2B2UMLw">http://amzn.to/2B2UMLw</a></p>
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<p>The post <a href="https://innohealthmagazine.com/2018/innovation/forecast-dengue-spread/">Forecast dengue spread</a> appeared first on <a href="https://innohealthmagazine.com">InnoHEALTH magazine</a>.</p>
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