Volume 7_Issue 4 Archives - InnoHEALTH magazine

Non-invasive Ventilators By Max Ventilator

InnoHEALTH magazine digital team — Mon, 11 Jul 2022 04:19:44 +0000

New multifunctional non-invasive (NIV) ventilators have recently been launched by Max Ventilator with built-in oxygen therapy and humidifier. The device is simple to use, is lightweight and offers unique multipurpose features. It is adaptable as it can be used both for newborn and adult. This device can also be used if a patient doesn’t require non-invasive ventilation but needs oxygen therapy. Thus it can do both non-invasive ventilation and oxygen treatment as a single unit. This is the USP of this product since so far there is no solution in the market which combines non-invasive ventilation and oxygen treatment. The NIV is portable and comes with a trolley which is 5 kgs in weight.

It is suitable to be used for patients suffering from COVID, pneumonia and neonates. For use in neonates, special kind of mask needs to be connected to the device thereby taking care of neonatal breathing difficulties immediately after birth. This aims to reduce the neonatal mortality rate.

There is an internal blending capability in the device for increasing the oxygen content from 31% to 100%. It also helps in the management of excess gases produced so that they do not affect other patients in the ICU. The NIV is equipped with a 7-inch touchscreen display and can save observed parameters and operational settings for 72 hours. It gives minimal damage to the user and has both BiPAP and CPAP modes making it suitable for usage by patients with sleep apnea also.

The uniqueness of this product lies in the fact that no cleaning is necessary and the device may be used by a second patient. The device is priced at a quarter of traditional ventilators. If an imported ventilator costs around 10-12 lacs INR , then this device costs only 25% of that amount. The company envisions that this device can reduce the requirement for critical ventilators by half. Thus is a potential game changer in the healthcare industry.

SOURCE: WWW.FINANCIALEXPRESS.COM

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Zero Assistance Integrated Digital Health Center Launched By IHL

InnoHEALTH magazine digital team — Thu, 07 Jul 2022 04:05:57 +0000

With a huge rural Indian population it is a gigantic task to provide accessibility of preventive and predictive health screening to the remotest areas of rural India where even primary healthcare facilities are scanty. But committed to handling this adverse condition is Health Link Pvt. Ltd., which has recently launched India Health Link (IHL) Care Digital Health Centre in Khagaria, Bihar making it the first-of-its-kind zero assistance Integrated Digital Health Centre (DHC) in the remote district of Khagaria with a population of more than 16 lakh people with almost 47% women inhabited in 306 villages. This Digital Health Centre also contains the world’s first Made in India Health Kiosk (Hpod) having multi-lingual compatibility with 12+ Indian languages with teleconsultation integrated with pharmacy and laboratory.

This facility will give the people of Khagaria a walk-in experience who can get their key vitals captured within 5 minutes and also get their unique IHL Health Accounts created which can also be integrated with Ayushman Bharat Health Account (ABHA) as it is the key to digital healthcare journey. This model aims to fill the healthcare delivery crisis which rural India is in dire need of as we have abysmally low doctor-patient ratio of 1:1456 and also of paramedics by helping the Anganwadi workers and ANMs to focus on their door to door visit programs.

IHL Care Digital Health Centre has developed a proprietary ‘hPOD’ which is a self-service ATM size health station capable of screening more than 20 essential vital parameters including temperature, pulse, blood pressure, SpO2, ECG and Body Mass Composition without medical assistance. The health pod will also allow teleconsultation withApollo TeleHealth doctors. The villagers will be aided to create their own electronic health records and take control of their wellness by making informed health choices.

SOURCE: WWW.EXPRESSHEALTHCARE.IN

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Advanced Prophylaxis Treatment For Hemophilic Patients

InnoHEALTH magazine digital team — Thu, 07 Jul 2022 04:05:20 +0000

Japanese Pharmaceutical giant, Takeda Pharmaceutical Company has launched an innovative extended half-life recombinant Factor VIII (Rfviii), ‘Adynovate’, using established technology (controlled PEGylation) for patients with haemophilia. Adynovate is administered in three steps with the BAXJECT III system, eliminating the need to disinfect the vial because vials are already assembled in the system housing.

This medicine in combination with MYPKFIT makes it the first and only FDA approved application, providing a tailored and interactive prophylaxis therapy option which allows both the patients and healthcare professionals to monitor factor VIII levels in real time. When the predicted factor VIII levels of haemophilic patients are low, an alert is sent to them and also reminders when their infusions are due. This feature gives a great prophylactic coverage of patients. The medicine can be stored for upto three months at room temperature without exceeding 30 degrees celsius/ 80 degree Fahrenheit.

SOURCE: WWW.BIOSPECTRUMINDIA.COM

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Once Daily, Single Inhaler-triple Therapy For Copd Patients

InnoHEALTH magazine digital team — Thu, 07 Jul 2022 04:04:21 +0000

In India COPD is estimated to affect more than 100 million people which accounts for more than 9.5 percent of all deaths. So an effective solution to its management is sought. Keeping this in mind, a market leader in pharmaceuticals, GlaxoSmithKline has recently launched one of the first once daily single-inhaler triple therapy (SITT) named “Trelegy Ellipta” (fluticasone furoate/umeclidinium/vilanterol) for Chronic Obstructive Pulmonary Disease (COPD) patients in India. Trelegy is administered through the innovative Ellipta inhaler which provides accurate dosage via its consistent dose delivery mechanism and is associated with less inhaler teaching time than other commonly used inhalers.

The product launch follows the approval by the Drugs Controller General of India (DGCI) of Trelegy Ellipta as a maintenance treatment to prevent and relieve symptoms associated with COPD in patients aged 18 and above.

SOURCE: PUBMED

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Weight loss threshold identified for cardiovascular and survival benefits in patients with obesity and diabetes

InnoHEALTH magazine digital team — Wed, 06 Jul 2022 04:22:00 +0000

Cleveland Clinic, America conducted an observational study on 1223 patients with obesity and type 2 diabetes who had undergone bariatric or weight loss surgery matched to 5978 patients who had usual medical care suffering from the above stated diseases. Nearly 80% patients had hypertension, 74% had dyslipidemia (increased cholesterol and triglycerides) and 31% were taking insulin for diabetic control. Different statistical models in relation to the effects of weight loss were then used to identify the minimum weight loss needed to decrease the risk of death and of experiencing major adverse cardiovascular events like heart failure, coronary artery events, cerebrovascular events , atrial fibrillation and kidney disease.

The study revealed that 5-10% of surgically induced weight loss is associated with improved life expectancy and cardiovascular health. In comparison to about 20% weight loss is necessary to observe similar results with a non-surgical treatment. In addition this research also displays that metabolic surgery may contribute to health benefits that are independent of weight loss.

The study suggests that greater heart disease benefits are achieved with less weight loss post metabolic surgery than the medical weight loss using lifestyle interventions. Since the groundbreaking STAMPEDE Study was revealed, many additional studies have followed that have observed health benefits other than weight loss following metabolic surgery. This research too is a secondary analysis of a large study that showed weight loss surgery is associated with a 40% reduction in risk of death and heart complications in obese and type 2 diabetic patients.

There are continuous studies going on to understand the physiological changes in the surgically modified gastrointestinal tract, the impact on hormone secretion and the microbiome. Those beneficial changes may contribute to the cardiovascular and survival benefits of metabolic surgery, independent of weight loss. Therefore more work needs to be done in this field to understand the underlying mechanisms for the health benefits of metabolic surgery in patients with obesity and type 2 diabetes.

SOURCE: WWW.MEDINDIA.NET

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‘Mind U’ – The Mental Health Podcast In Hinglish

InnoHEALTH magazine digital team — Wed, 06 Jul 2022 04:21:00 +0000

As per the National Mental Health Survey, depression is a mental illness that affects one in 20 indians. A frontrunner in the management of ill mental health is Fortis Healthcare in which it runs one of the most comprehensive and biggest mental health programmes in India under the leadership of Dr. Parikh and myUpchar is India’s biggest healthtech startup. Not much substantial work has been done in the field of mental health in India especially in a language which is comprehensible by most of the Indian population. Keeping this lacunae in mind upChar has created “Mind U’ a first-of-its-kind deep dive into mental health and wellness podcast in Hinglish that is in a language that is accessible to most Indians and to many Indians living abroad in collaboration with Dr. Parikh and a team of experts from Fortis.

On this podcast leading experts under the leadership of Dr. Parikh will take listeners through crucial aspects of psychological well-being in 20 minutes or less speaking on topics ranging from clinical disorders like depression, deepdive into parenting to topics related to youth like relationships, sexuality and social media. The episodes of Mind U will be telecast on Apple podcasts, Google podcasts, Castbox, YouTube, Spotify, JioSaavn and HubHopper. In each episode the experts will answer a series of questions on the topic du jour and the topics range from parenting 101 to breaking up without breaking down. Listeners can expect an in depth discussion about things which we all can relate to, that happen to us in our day today life like effective handling and navigation of social media and maintaining our relations even as our lives become busier and busier.

Listeners will be guided to see the connection between the things we do every day and our mental health. It is indeed a much needed step in this direction and we applaud the efforts made by Fortis Healthcare and myUpchar.

SOURCE: HEALTHVISION.IN

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New Communication Discovered Between Human Embryos And Mother

InnoHEALTH magazine digital team — Wed, 06 Jul 2022 04:20:00 +0000

A team of researchers at The University of Manchester and Manchester University NHS Foundation Trust conducted an in vitro research which exhibited a new way human embryos communicate with their mother-to-be just after six days of its development. The study also put light on the fact that the embryos could detect foreign cells in their environment including pathogens. Early human embryos are highly sensitive to their local environment but before this study, relatively less was known about how they detect and respond to specific environment cues.

This study has discovered a signalling system which is generated by the embryo which allows communication with mother in a new way wherein it was found that when foreign cells are detected by the embryos’ special proteins called Toll Like Receptors(TLRs), cytokines (IL8) are produced which typically plays a role in the body’s immune system by engaging neutrophils to the inflammation site. The team examined the behaviour of the embryo throughout the fifth and sixth days of the embryos’ development wherein it is free-living in the female body before implanting into the uterus lining.

It is already known that embryos communicate with mothers when they begin to implant but we do not know why this above-mentioned new signalling happens. Perhaps this presence of TLRs in the fallopian tube and vagina is an additional way of signalling an inflammatory response to the maternal tract in response to pathogens or to modulate the implantation process and the initiation of pregnancy.

The team used a literature search of published data to analyse the expression of TLRs and related genes in human embryos. Then they cultured 25 days old human embryos in the presence of poly (I:C) and flagellin which attach to the toll-like receptors TLR3 and TLR5. EThe team only investigated TLR 3 and 5 and on the sixth day, they measured gene expression and cytokine production to compare the results with the controls.

The data also reveals that there is a balance between suppression and stimulation of the innate immunity response in embryos. That may reflect the need for embryo survival in the presence of benign foreign cells versus the need for maternal tract to respond to infection. This groundbreaking research may help to understand fertility issues, helping people who struggle to achieve natural conception and even enhancing IVF methods. The research is published in the Journal Human Reproduction Today. Still further investigations need to be done to determine whether the TLR stimulation response is effective during the embryonic journey in the fallopian tube.

SOURCE: WWW.HEALTHEUROPA.EU

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