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Researchers at the Ohio State University, Wexner Medical Center and Ohio state’s College of Engineering have developed a new technology, Tissue Nano Transfection (TNT), that can generate any cell type of interest for treatment within the patient’s own body with a single touch. This TNT does not require any laboratory-based procedures and may be implemented at the point of care. This technology may be used to repair injured tissue or restore function of aging tissue, including organs, blood vessels and nerve cells. Results of the regenerative medicine study is published in the journal Nature Nanotechnology.

Researchers studied mice and pigs in their experiments where they were able to reprogram skin cells to become vascular cells in badly injured legs that lacked blood flow. Within one week, active blood vessels appeared in the injured leg and by the second week, the leg was saved. The technology was also shown to reprogram skin cells in the live body into nerve cells that were injected into brain-injured mice to help them recover from stroke.

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